Bioresorbable scaffolds for percutaneous coronary interventions

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Bioresorbable scaffolds for percutaneous coronary interventions

UNLABELLED Innovations in drug-eluting stents (DES) have substantially reduced rates of in-segment restenosis and early stent thrombosis, improving clinical outcomes following percutaneous coronary interventions (PCI). However a fixed metallic implant in a vessel wall with restored patency and residual disease remains a precipitating factor for sustained local inflammation, in-stent neo-atheros...

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Recommendations for the use of bioresorbable vascular scaffolds in percutaneous coronary interventions

BACKGROUND To eliminate some of the potential late limitations of permanent metallic stents, the bioresorbable coronary stents or 'bioresorbable vascular scaffolds' (BVS) have been developed. METHODS We reviewed all currently available clinical data on BVS implantation. RESULTS Since the 2015 position statement on the appropriateness of BVS in percutaneous coronary interventions, several la...

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Current status of clinically available bioresorbable scaffolds in percutaneous coronary interventions

Drug-eluting stents (DES) are widely used as first choice devices in percutaneous coronary interventions. However, certain concerns are associated with the use of DES, i.e. delayed arterial healing with a subsequent risk of neo-atherosclerosis, late stent thrombosis and hypersensitivity reactions to the DES polymer. Bioresorbable vascular scaffolds are the next step in percutaneous coronary int...

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Appropriate use of bioresorbable vascular scaffolds in percutaneous coronary interventions: a recommendation from experienced users

Percutaneous coronary interventions (PCI) have become a reliable revascularisation option to treat ischaemic coronary artery disease. Drug-eluting stents (DES) are widely used as first choice devices in many procedures due to their established good medium to long term outcomes. These permanent implants, however, do not have any residual function after vascular healing following the PCI. Beyond ...

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Bioresorbable Vascular Scaffolds for Coronary Revascularization.

Contemporary metallic drug-eluting stents are associated with very good 1-year outcomes but an ongoing risk of stent-related adverse events (thrombosis, myocardial infarction, restenosis) after 1 year. The pathogenesis of these very late events is likely related to the permanent presence of the metal stent frame or polymer. Bioresorbable scaffolds have been developed to provide drug delivery an...

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ژورنال

عنوان ژورنال: Global Cardiology Science and Practice

سال: 2014

ISSN: 2305-7823

DOI: 10.5339/gcsp.2014.55